The Bills won their third straight game, surprising the 49ers with a solid running game and another good defensive effort. The Bills climbed to 5-2 with the win, dropping the 49ers to 5-2 in the process. The Bills got off to a fast start, driving down the field and scoring on a 9 yard TD run by Marshawn Lynch. Then, on the 49ers first play from scrimmage, LE Phillip Merling sacked Nate Davis and knocked the ball loose, leading to RE Alex Carrington picking it up and rumbling into the endzone from 18 yards out. San Fran wouldn't make the same mistake on their next drive however, Davis finding stud WR Broderick Cotton for the 39 yard TD. 14-7 Bills after the first quarter. The Bills would quickly score again, Tyler Dougherty hitting wide open TE Derek Schouman for the 8 yard TD. Super fast safety Taylor Mays would answer with two interceptions leading to 10 points for the 49ers, first on a 11 yard pass to TE Vernon Davis and then on a field goal as time expired. The Bills still lead 21-17 at the half, but the 49ers were looking like the better team. Dougherty would turn it on in the second half, making a perfect throw to Randy Moss for a 65 yard TD in the third, then finding CJ Spiller on a screen early in the fourth for a 71 yard TD of his own. Another Vernon Davis TD would cut the margin to 11 points, but some great defense and a late field goal sealed the win for the Bills, finally ending up winning 38-24 after their best performance of the season. Game MVP was rookie QB Dougherty, who bounced back from two early interceptions to finish with 272 yards and 3 TD's on 14/20 passes. Spiller was his usual self, finishing with 154 yards and 1 TD from scrimmage. Mays was the best for San Fran, making 4 tackles to go along with his 2 picks. GG Gaddy, always fun playing you.